Elizabeth Tullis Selected Research

tezacaftor

1/2023	Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials.
1/2022	Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
1/2021	A phase 3, randomized, double-blind, parallel-group study to evaluate tezacaftor/ivacaftor in people with cystic fibrosis heterozygous for F508del-CFTR and a gating mutation.
11/2019	Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
1/2018	Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR.
11/2017	Tezacaftor-Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis.

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Elizabeth Tullis Research Topics

Disease

68	Cystic Fibrosis (Mucoviscidosis) 05/2024 - 06/2001
14	Infections 12/2020 - 06/2001
12	Lung Diseases (Lung Disease) 04/2022 - 01/2003
3	Glucose Intolerance 02/2019 - 02/2005
3	Hyperglycemia 04/2010 - 02/2005
3	Exocrine Pancreatic Insufficiency 03/2005 - 01/2003
2	Weight Gain 01/2023 - 03/2017
2	Diabetes Mellitus 01/2020 - 02/2005
2	Persistent Infection 01/2020 - 06/2001
2	Body Weight (Weight, Body) 03/2017 - 04/2010
2	Pancreatitis 03/2014 - 01/2011
2	Respiratory Tract Diseases (Respiratory Tract Disease) 07/2013 - 01/2009
2	Inflammation (Inflammations) 07/2013 - 01/2009
1	Apnea 12/2023
1	Pancreatic Diseases (Pancreatic Disease) 12/2023
1	Meconium Ileus 12/2023
1	Intestinal Obstruction (Obstruction, Intestinal) 12/2023
1	Exanthema (Rash) 01/2023
1	Frailty 11/2022
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2022
1	Psychotic Disorders (Schizoaffective Disorder) 01/2022
1	Headache (Headaches) 11/2021
1	Burkholderia Infections 12/2020
1	Asthma (Bronchial Asthma) 01/2020
1	Malnutrition (Nutritional Deficiencies) 01/2020
1	Allergic Bronchopulmonary Aspergillosis 01/2020
1	Hypoxia (Hypoxemia) 09/2018
1	Abdominal Pain (Pain, Abdominal) 03/2017
1	Venous Thromboembolism 05/2015
1	Azoospermia 03/2014
1	Thrombosis (Thrombus) 09/2011
1	Hyperlipidemias (Hyperlipidemia) 02/2011
1	Respiratory Insufficiency (Respiratory Failure) 02/2011
1	Dyslipidemias (Dyslipidemia) 01/2010
1	Weight Loss (Weight Reduction) 10/2009
1	Bacterial Infections (Bacterial Infection) 07/2009
1	Venous Thrombosis (Deep-Vein Thrombosis) 03/2009
1	Vitamin D Deficiency 05/2007
1	Bone Diseases (Bone Disease) 03/2005

Drug/Important Bio-Agent (IBA)

13	ivacaftor drug combination tezacaftorIBA 12/2023 - 11/2017
12	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 06/2001
11	elexacaftorIBA 12/2023 - 10/2018
8	ChloridesIBA 12/2023 - 01/2011
8	ivacaftorIBA 01/2023 - 11/2011
8	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2022 - 11/2011
6	tezacaftorIBA 01/2023 - 11/2017
4	Glucose (Dextrose)FDA LinkGeneric 02/2019 - 02/2005
4	Tobramycin (Nebcin)FDA LinkGeneric 01/2019 - 01/2015
3	EnzymesIBA 01/2020 - 01/2003
3	dornase alfa (Pulmozyme)FDA Link 11/2015 - 01/2009
2	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2021
2	Bicarbonates (Hydrogen Carbonate)IBA 03/2017 - 03/2006
2	neodymium pyrocatechin disulfonate (NPD)IBA 05/2015 - 03/2014
2	Sulfhydryl Compounds (Thiols)IBA 07/2013 - 01/2009
2	Vitamin A (Retinol)FDA LinkGeneric 09/2011 - 03/2005
2	Proteins (Proteins, Gene)FDA Link 09/2011 - 02/2005
2	LipidsIBA 02/2011 - 01/2010
2	Insulin (Novolin)FDA Link 10/2009 - 02/2005
2	VitaminsIBA 03/2005 - 03/2005
1	Prednisone (Sone)FDA LinkGeneric 05/2024
1	TrypsinogenIBA 12/2023
1	riociguatIBA 11/2021
1	Expectorants (Mucolytics)IBA 01/2020
1	Omalizumab (Xolair)FDA Link 01/2020
1	AnionsIBA 04/2019
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 02/2019
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2019
1	VX-659IBA 10/2018
1	Oxygen (Dioxygen)IBA 09/2018
1	PowdersIBA 07/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2015
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 05/2015
1	SteroidsIBA 05/2015
1	Ion Channels (Ion Channel)IBA 05/2014
1	Adrenergic Agents (Adrenergic Drugs)IBA 10/2012
1	galactomannanIBA 08/2012
1	prednylidene (Pred)IBA 01/2012
1	LDL Receptors (LDL Receptor)IBA 09/2011
1	Insulin Aspart (NovoLog)FDA Link 10/2009
1	repaglinide (Prandin)FDA Link 10/2009
1	Peptides (Polypeptides)IBA 07/2009
1	Vitamin D FDA LinkGeneric 05/2007
1	hydroxide ionIBA 05/2007
1	25-hydroxyvitamin DIBA 05/2007
1	Cholecalciferol (Vitamin D3)FDA Link 05/2007
1	Capsules (Microcapsules)IBA 03/2006
1	Gonadal Steroid Hormones (Sex Hormones)IBA 03/2005
1	GlucocorticoidsIBA 03/2005
1	CytokinesIBA 03/2005
1	Fimbriae Proteins (Pilin)IBA 05/2004

Therapy/Procedure

20	Therapeutics 12/2023 - 02/2005
12	Lung Transplantation 11/2022 - 01/2003
5	Transplantation 12/2020 - 01/2003
1	High-Protein Diet 01/2020
1	Noninvasive Ventilation 09/2018
1	Aftercare (After-Treatment) 03/2017
1	Precision Medicine 10/2016
1	Respiratory Therapy (Therapy, Respiratory) 05/2015
1	Catheters 03/2009
1	Ambulatory Care (Outpatient Care) 01/2006